Weber-Christian disease, A Rare disease, and Successful Treatment Using Prednisolone and Colchicine: A Case Report from Nigeria and Literature Review
Abstract
Weber Christian disease (WCD) is a rarely reported medical condition. It is an idiopathic lobular panniculitis,
which is characterized by subcutaneous nodules, inflammatory cells in the fat lobules, and systemic
symptoms. The literature has a handful of reports of WCD from different regions of the globe since the first
descriptions by Pfeifer in 1892 and later in the 1920s by Weber and Christian. We report the first Nigerian
case from the South East region of WCD. Being a rare entity, there were challenges with arriving at a
diagnosis and successful treatment eventually with colchicine and low-dose prednisolone. Hence, this
report.
Keywords: Weber Christian Disease, Treatment, Colchicine, Prednisolone
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